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Rh he had not taken arsenic; and as the affection responded to quinine so readily it was diagnosed by Sir Patrick Manson, and also Dr Buzzard, who saw the case, as peripheral neuritis, directly due to sub-tertian malaria. (Only a blood examination could have put one on the right track here.)

Case 29. J. H.., [sic] 44, from the Gold Coast. Admitted with an unhealthy granulating wound on the head and a sinus leading to bone on the right temporal, received at the hands of some natives on the Gold Coast. Temperature rose to 102.4° on admission, with a rigor, and the onset of septicæmia was suspected. Blood was examined and benign tertian parasites were found. Quinine was consequently injected and a straightforward recovery ensued, the wound healing up rapidly.

Case 30. J. W. C., 44, from Calcutta. Admitted, 1st November 1906. In March 1906 was taken ill with what was supposed at first to be enteric. Had sweats at intervals and then irregular fevers set in and malaria was diagnosed. Spleen became enlarged. He took quinine, grs. xx. to grs. xxx., daily, with little effect, and continued this until