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within the last decade has the examination of the blood been resorted to in disease, as an aid both to diagnosis and, in a lesser degree, to prognosis. Each year this method of investigation has achieved fresh importance, each year we have learnt more fully how to appreciate the significance of the changes seen microscopically, as well as the value of serum reactions, cultures from blood and alterations in its chemistry.

So great has the advance been in this direction that nowadays, in any obscure "case," until examination of the blood has been performed, we should not feel that every means, not only of information, but of possibly most valuable information, had been employed.

If this is true of disease at home here in