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Utero-placental infection.—In 's case, a man who claimed to have been exposed in sexual intercourse but once in two years, presented himself three weeks after the latter occurrence with indurated chancre of the glans. Regular intercourse meanwhile was had with the wife, who, when examined, was found to have a genital sore newly developed between the third and fourth month of pregnancy. This in due time was followed by constitutional symptoms. The child when born was covered with skin lesions, had nodes on most of the long bones, and lived but two weeks. It was preceded by the birth of a healthy child, and followed by a miscarriage.

Such an exceptional history, of course, requires the fullest confirmation by several observers.—''Amer. Practitioner'', March, 1880.

Case of congenital syphilis derived directly from the father; immunity of the mother during gestation; subsequent infection of the latter by her offspring.—The following details of an interesting case are furnished by Prof. : "A healthy and fine-looking girl, 19 years of age, without previous history of disease, of irreproachable habits, and descended from a family where there is no suspicion of syphilis, was married in December of 1874 to a vigorous and comely young man, who had lately left the military service, where, though consecrated to Mars, he had not neglected to sacrifice to Venus. In return he suffered from ulcers, and an adenopathy which was regarded as suspicious because it did not result in suppuration. This disorder was treated