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NAME HOLMES 541 HOLMES of the hospital service at Richmond, Virginia, where he remained until the close of the war. He then came to Louisville and was appointed professor of anatomy in the University of Louisville, at the end of one year being trans- ferred to the chair of physiology ond medical jurisprudence which he resigned in 1867. Among other appointments he had the pro- fessorship of clinical and operative surgery in the Kentucky School of Medicine and also in the Louisville Medical College ; also the chair of surgery in the latter institution for eight years, resigning to accept the same chair in the Louisville Medical College and the Ken- tucky School of Medicine. In 1898 he was professor of surgery in the Kentucky Uni- versity, medical department, a position he held until his death, and in 1885 Centre College con- ferred upon him the M. A. degree. His most noted writing was a contribution to '"Surgery by American Authors," edited by Roswell Park, upon "Diseases of the Veins." Dr. Holloway gave his practice the closest attention and was renowned for his prompt- ness in meeting all engagements. Although a great sufferer from gout, rarely did it keep him from work, and it was no unusual sight to see him visiting patients with his foot swathed in flannels. He was very much be- loved by his clientele and generally well liked by the profession. It is claimed that Dr. Holloway was the physician who suggested to the late Emil SchefTer, the pioneer manu- facturer of pepsin, the substitution of the pep- sin from the hog's stomach instead of that of the calf as an aid to digestion. In 1858 Hollo- way married Annie Warren and had five chil- dren, one of whom, Samuel Warren, also be- came a doctor. J. G.^RLAND ShERRIL. Amer. Tour. Med. Assoc, 1905, vol. xlv, 1671. South. "Pract., Nashville, 1905. vol. xxvii, 700- 702. Holmes, Andrew Fernando (1797-1860). Andrew Fernando Holmes was born in Cadiz, a contingency which arose from the capture by a French frigate of the ship in which his parents were sailing for Canada. Four years later he arrived in Montreal, and at fifteen began his medical studies under Arnold pcre. In 1819 he graduated at Edin- burgh, then went to Paris for further study and returned to Canada where he was ap- pointed physician to the Montreal General Hospital in 1821, the year of its foundation. He aided in founding the Montreal School of Medicine in 1824. After 1828 this became the medical department of McGill University. Holmes filled the chair of materia medica and chemistry till 1836, then that of chemistry alone till 1842, and was subsequently pro- fessor of theory and practice of medicine. Dur- ing the last eight years of his life he was |. dean of the Medical Faculty of McGill, and died suddenly on October 9, 1860. Many of Dr. Holmes' writings are yet extant. Among them are his graduating thesis, "De Tetano"; papers upon "Intrauterine Crying of the Child"; "Fleshy Tubercle of the Uterus"; "Asiatic Cholera in Montreal"; "A Case of the Employment of Chloroform," Brilish Medical Journal (vol. iii). He was one of the founders of the Natural History Society of Montreal and presented his herbarium to the University. Andrew M.^cph.'^il. Holmes, Edward Lorenzo (1828-1900). Edward Lorenzo Holmes, born January 28, 1828, at Dedham, Massachusetts, graduated from Harvard College at the age of twenty- one and then taught in the Latin School of Roxbury, Massachusetts. He graduated in medicine at Harvard in 1854, later serving as interne in the Massachusetts General Hospital. After spending two years in Vienna he took up the practice of ophthalmology and otology in Chicago. He was a founder of the Illinois Charitable Eye and Ear Infirmary, and the head of its surgical staff until his death. He was also a founder of the Presbyterian Hos- pital and later one of its surgeons. In 1860 he became lecturer on ophthalmology and otology in Rush Medical College, and was elected to a full professorship in 1867, in 1890 being elected president of the college, retaining this position until he resigned from the faculty on his seventieth birthday. He was a member of the American Ophthalmological Soiciety for many years. One of the pioneers of ophthalmology in the West, he exerted a powerful influence there. He died of pneumonia, February 12, 1900, in Chicago. H.-RRY FrIEDENWALD. Trans. .-Nmer. Ophth. Soc. vol. ix. Tour. Amer. Med. Assoc. 1900, vol. .xxxiv. "Ophth. Rec, 1898, vol. vii. Trans. .Amer. Ophth. Soc, vol. ix. Portrait. Holmes, Horatio Reese (1856-1896). Horatio Reese Holmes, a man who bade fair to be the leading pioneer gynecologist of the northwestern States, was born in Polk Coun- ty, Oregon, July 30, 18.56, the son of Horatio Nelson Viscount and Nancy Porter Holmes. He was the youngest of five brothers. His ancestors came from the north of Ireland. He