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 To find out the Subject Cause of this Venenum Terroris, a Disease most notorious for its Cruelty, Malignity, and dubious Event; generated here with us, by Foreign Assistance, and where-ever it diffuses its Contagion, it invades the very Capital of the Soul, and stifles the animal Spirits.

Most Physicians will have the Heart to be the chief Seat or Subject of this Contagious Distemper, from whence all preternatural Heat is communicated to the rest of the Body; and this, they say, is demonstrable from the Pulse, which proceedeth from the Action of the Heart, and the pulsifick Faculty, and fiery Spirits, mix'd with the arterious Blood.

Sir George Ent, and Dr. Sydenham, place the Seat of this Disease in the Blood: For as in Wine and Milk, we observe strange Disturbances and Fermentations, Why may there not happen the same in the Mass of Blood? Nor are the animal Spirits to be excluded. The secondary and more general Subject of this Pestilential Fever, are all the Parts, in that the Disease, by the help of the Arteries, invadeth the whole Body.

There are almost as many Opinions as Physicians, concerning the Cause of this terrible Disease; tho', for the Generality, they agree in the Description of it: Which is, That it is a continual Epidemick Fever, that privately and lurkingly seizeth upon Human Rh