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 The figure of the tree of life the fruit of which brings immortality, is, as Pro 11:30; Pro 15:4 (cf. Pro 13:12), Rev 2:7, taken from the history of paradise in the Book of Genesis. The old ecclesiastical saying, Lignum vitae crux Christi, accommodates itself in a certain measure, through Mat 11:19; Luk 11:49, with this passage of the Book of Proverbs. החזיק ב means to fasten upon anything, more fully expressed in Gen 21:18, to bind the hand firm with anything, to seize it firmly. They who give themselves to Wisdom, come to experience that she is a tree of life whose fruit contains and communicates strength of life, and whoever always keeps fast hold of Wisdom is blessed, i.e., to be pronounced happy (Psa 41:3, vid., under Psa 137:8). The predicate מאשּׁר, blessed, refers to each one of the תּמכיה, those who hold her, cf. Pro 27:16; Num 24:9. It is the so-called distributive singular of the predicate, which is freely used particularly in those cases where the plur. of the subject is a participle (vid., under Pro 3:35).

Verses 19-20
This place of a mediatrix - the speaker here now continues - she had from the beginning. God's world-creating work was mediated by her: 19 Jahve hath by wisdom founded the earth,     Established the heavens by understanding.